Soman N. Abraham, Ph.D. Laboratory
Ashley St. John, BS (Georgia Tech), PhD
Immunology Graduate Program (2005-2010)
Current Position: Assistant Professor,
Program in Emerging Infectious Diseases, Duke-NUS
Publications from the Abraham lab.
John, A. L. S., Ang, W. G., Huang, M. N., Kunder, C. A., Chan, E. W., Gunn, M. D., & Abraham, S. N. (2014). S1P-Dependent trafficking of intracellular yersinia pestis through lymph nodes establishes Buboes and systemic infection. Immunity, 41(3), 440-450.
John, A. L. S., Abraham, S. N., & Gubler, D. J. (2013). Barriers to preclinical investigations of anti-dengue immunity and dengue pathogenesis. Nature Reviews Microbiology, 11(6), 420-426.
St John, A. L., Rathore, A. P., Raghavan, B., Ng, M. L., & Abraham, S. N. (2013). Contributions
of mast cells and vasoactive products, leukotrienes and chymase, to dengue virus-induced vascular leakage. Elife, 2, e00481.
John, A. L. S., & Abraham, S. N. (2013). Innate immunity and its regulation by mast cells. The Journal of Immunology, 190(9), 4458-4463.
Chan, C. Y., John, A. L. S., & Abraham, S. N. (2013). Mast cell interleukin-10 drives localized tolerance in chronic bladder infection. Immunity, 38(2), 349-359.
John, A. L. S., Chan, C. Y., Staats, H. F., Leong, K. W., & Abraham, S. N. (2012). Synthetic mast-cell granules as adjuvants to promote and polarize immunity in lymph nodes. Nature materials, 11(3), 250-257.
Chan, C. Y., John, A. L. S., & Abraham, S. N. (2012). Plasticity in mast cell responses during bacterial infections. Current opinion in microbiology, 15(1), 78-84.
Kunder, C. A., St John, A. L., & Abraham, S. N. (2011). Mast cell modulation of the vascular and lymphatic endothelium. Blood, 118(20), 5383-5393.
John, A. L. S., Rathore, A. P., Yap, H., Ng, M. L., Metcalfe, D. D., Vasudevan, S. G., & Abraham, S. N. (2011). Immune surveillance by mast cells during dengue infection promotes natural killer (NK) and NKT-cell recruitment and viral clearance. Proceedings of the National Academy of Sciences, 108(22), 9190-9195.
Abraham, S. N., & John, A. L. S. (2010). Mast cell-orchestrated immunity to pathogens. Nature Reviews Immunology, 10(6), 440-452.
St John, A. L., & Abraham, S. N. (2009). Salmonella disrupts lymph node architecture by TLR4-mediated suppression of homeostatic chemokines. Nature medicine, 15(11), 1259-1265.
Shelburne, C. P., Nakano, H., John, A. L. S., Chan, C., McLachlan, J. B., Gunn, M. D., ... & Abraham, S. N. (2009). Mast cells augment adaptive immunity by orchestrating dendritic cell trafficking through infected tissues. Cell host & microbe, 6(4), 331-342.
Kunder, C. A., John, A. L. S., Li, G., Leong, K. W., Berwin, B., Staats, H. F., & Abraham, S. N. (2009). Mast cell–derived particles deliver peripheral signals to remote lymph nodes. The Journal of experimental medicine,206(11), 2455-2467.